ITGAX monoclonal antibody, clone 5D11
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining for paraffin-embedded human hairy cell leukemia section using ITGAX monoclonal antibody, clone 5D11 (Cat # MAB9562). Note membrane staining of malignant cells.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant ITGAX.
Immunogen
Recombinant protein corresponding to 258 amino acids near N-terminus of ITGAX .
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2a
Recommend Usage
Immunohistochemistry (1:80)
The optimal working dilution should be determined by the end user.Storage Buffer
In tissue culture supernatant (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining for paraffin-embedded human hairy cell leukemia section using ITGAX monoclonal antibody, clone 5D11 (Cat # MAB9562). Note membrane staining of malignant cells. -
Gene Info — ITGAX
Entrez GeneID
3687Gene Name
ITGAX
Gene Alias
CD11C, SLEB6
Gene Description
integrin, alpha X (complement component 3 receptor 4 subunit)
Omim ID
151510Gene Ontology
HyperlinkGene Summary
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq
Other Designations
OTTHUMP00000163299|integrin alpha X|integrin, alpha X (antigen CD11C (p150), alpha polypeptide)|leu M5, alpha subunit|leukocyte surface antigen p150,95, alpha subunit|myeloid membrane antigen, alpha subunit|p150 95 integrin alpha chain
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Interactome
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Pathway
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Disease
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