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Last updated: 2016/12/4
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NPM1 monoclonal antibody, clone 7H10B9

  • Catalog # : MAB8313
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant NPM1.
  • Immunogen:
  • Recombinant protein corresponding to human NPM1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:2000)
    Immunohistochemistry (Frozen sections) (1:500-1:2000)
    ELISA (1:10000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Wetern blot analysis of SMMC-7721 cell extracts with NPM1 monoclonal antibody, clone 7H10B9 (Cat # MAB8313).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis pf paraffin-embedded human liver carcinoma, showing nuclear localization using NPM1 monoclonal antibody, clone 7H10B9 (Cat # MAB8313) with DAB staining.
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4869
  • Gene Name:
  • NPM1
  • Gene Alias:
  • B23,MGC104254,NPM
  • Gene Description:
  • nucleophosmin (nucleolar phosphoprotein B23, numatrin)
  • Gene Summary:
  • NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF (MIM 600160). NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia (AML; MIM 601626) (Garzon et al., 2008 [PubMed 18308931]).[supplied by OMIM
  • Other Designations:
  • nucleolar phosphoprotein B23,nucleophosmin 1,nucleophosmin/nucleoplasmin family, member 1,numatrin
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