SELE monoclonal antibody, clone ELAM-1
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Specification
Product Description
Mouse monoclonal antibody raised against native SELE.
Immunogen
Native purified SELE from human neutrophils.
Host
Mouse
Theoretical MW (kDa)
115
Reactivity
Human
Specificity
This antibody is specific to the human antigen E-selectin (ELAM-1, 115 KDa).
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (10 mM sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — SELE
Entrez GeneID
6401Gene Name
SELE
Gene Alias
CD62E, ELAM, ELAM1, ESEL, LECAM2
Gene Description
selectin E
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq
Other Designations
OTTHUMP00000032745|endothelial adhesion molecule 1|leukocyte endothelial cell adhesion molecule 2
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Interactome
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Pathway
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Disease
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