E-Selectin monoclonal antibody, clone hCD62E
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of human E-Selectin.
Immunogen
Purified, Activated T-Cells
Host
Mouse
Form
Lyophilized
Purification
Ion-Exchange Column
Isotype
IgG1
Recommend Usage
For staining (10 µL/1,000,000 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 1 mg/mL in PBS
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with 1 mL of deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — SELE
Entrez GeneID
6401Gene Name
SELE
Gene Alias
CD62E, ELAM, ELAM1, ESEL, LECAM2
Gene Description
selectin E
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq
Other Designations
OTTHUMP00000032745|endothelial adhesion molecule 1|leukocyte endothelial cell adhesion molecule 2
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