PROC monoclonal antibody, clone HLW-C
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Specification
Product Description
Mouse monoclonal antibody raised against native PROC.
Immunogen
Native purified human blood PROC.
Host
Mouse
Reactivity
Human
Form
Lyophilized
Isotype
IgG2b, kappa
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
Lyophilized from 10 mM PBS, pH 7.2
Storage Instruction
Store at -20°C.
Aliquot after reconstitution to avoid repeated freezing and thawing. -
Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — PROC
Entrez GeneID
5624Gene Name
PROC
Gene Alias
PC, PROC1
Gene Description
protein C (inactivator of coagulation factors Va and VIIIa)
Omim ID
176860Gene Ontology
HyperlinkGene Summary
The PROC gene encodes protein C (EC 3.4.21.69), a vitamin K-dependent plasma glycoprotein that is a key component of the anticoagulant system. Protein C is cleaved to its activated form, 'activated protein C' (APC) on endothelial cells by the thrombin-thrombomodulin complex (MIM 176930; MIM 188040) and then acts as a serine protease to degrade the activated forms of coagulation factors V (F5; MIM 612309) and VIII (F8; see MIM 306700). Protein S (PROS1; MIM 176880), also a vitamin K-dependent plasma protein, functions as a cofactor to activated protein C.[supplied by OMIM
Other Designations
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Interactome
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Pathway
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Disease
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