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Last updated: 2017/12/10
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F10 monoclonal antibody, clone F10-1

  • Catalog # : MAB6382
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against F10.
  • Immunogen:
  • Human F10.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Lyophilized
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 10 mM PBS, pH 7.2
  • Storage Instruction:
  • Store at -20°C.
    Aliquot after reconstitution to avoid repeated freezing and thawing.
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2159
  • Gene Name:
  • F10
  • Gene Alias:
  • FX,FXA
  • Gene Description:
  • coagulation factor X
  • Gene Summary:
  • This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000018735,Stuart-Prower factor,factor Xa,prothrombinase
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