F10 recombinant monoclonal antibody, clone 3F2
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Immunohistochemistry
Immunohistochemistry image of F10 recombinant monoclonal antibody, clone 3F2 diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human F10.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to full length human F10.
Reactivity
Human
Form
Liquid
Purification
Affinity-chromatography
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry image of F10 recombinant monoclonal antibody, clone 3F2 diluted at 1:100 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
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Gene Info — F10
Entrez GeneID
2159Protein Accession#
P00742Gene Name
F10
Gene Alias
FX, FXA
Gene Description
coagulation factor X
Omim ID
227600Gene Ontology
HyperlinkGene Summary
This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq
Other Designations
OTTHUMP00000018735|Stuart-Prower factor|factor Xa|prothrombinase
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Interactome
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