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Last updated: 2017/12/10
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ICAM1 monoclonal antibody, clone 15.2 (Biotin)

  • Catalog # : MAB5507
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native ICAM1.
  • Immunogen:
  • A mixture of native ICAM1 from Rheumatoid synovial cells and human monocytes.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Recognizes the (Mr 85-115KDa) intercellular adhesion molecule ICAM-1 which permits antigen-independent adhesion between lymphocytes and their targets. The LFA-1 binding site is located in domain 1 of ICAM-1. ICAM-1 is a membrane glycoprotein with a wide tissue distribution that includes vascular endothelium and many cells of the immune system. CD54 is weakly expressed on resting peripheral blood lymphocytes. Upon activation by mitogens, the CD54 antigen is strongly expressed on B-cells, T-cells, macrophages and granulocytes. CD54 is the receptor for rhinoviruses and malaria
  • Form:
  • Liquid
  • Conjugation:
  • Biotin
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow Cytometry (using 1ug to stain 1 x 106 cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.2 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Flow Cytometry
  • Application Image
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3383
  • Gene Name:
  • ICAM1
  • Gene Alias:
  • BB2,CD54,P3.58
  • Gene Description:
  • intercellular adhesion molecule 1
  • Gene Summary:
  • This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq
  • Other Designations:
  • cell surface glycoprotein P3.58,human rhinovirus receptor,intercellular adhesion molecule 1 (CD54), human rhinovirus receptor
  • Interactome
  • Interactome
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