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Last updated: 2017/12/10
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THBD monoclonal antibody, clone QBEND/40

  • Catalog # : MAB5235
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against THBD.
  • Immunogen:
  • Human THBD.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody recognizes all human endothelium tested. Preliminary evidence suggests that this antibody recognizes Thrombomodulin, but does not inhibit Thrombomodulin dependent activation of protein C.
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Flow Cytometry (10ul of the suggested working dilution (neat) to label 106 cells in 100ul)
    Immunohistochemistry (Frozen sections) (1:10-1:100)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:10-1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In tissue culture supernatant (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 7056
  • Gene Name:
  • THBD
  • Gene Alias:
  • CD141,THRM,TM
  • Gene Description:
  • thrombomodulin
  • Gene Summary:
  • The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq
  • Other Designations:
  • CD141 antigen,OTTHUMP00000030415,fetomodulin
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