THBD recombinant monoclonal antibody, clone 15C7
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human THBD.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human THBD.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry(1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry image of THBD recombinant monoclonal antibody, clone 15C7 diluted at 1:100 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
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Gene Info — THBD
Entrez GeneID
7056Protein Accession#
P07204Gene Name
THBD
Gene Alias
CD141, THRM, TM
Gene Description
thrombomodulin
Omim ID
188040Gene Ontology
HyperlinkGene Summary
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq
Other Designations
CD141 antigen|OTTHUMP00000030415|fetomodulin
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Interactome
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Pathway
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Disease
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