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Last updated: 2016/10/23
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TNFRSF10C monoclonal antibody, clone TRAIL-R3-02 (PE)

  • Catalog # : MAB5138
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant TNFRSF10C.
  • Immunogen:
  • Recombinant Fc fusion protein corresponding to amino acids 1-280 of TNFRSF10C.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 35
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with TRAIL-R3, a 35 KDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.
  • Form:
  • Liquid
  • Conjugation:
  • PE
  • Concentration:
  • 0.1 mg/mL
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow Cytometry (3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.2% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store in the dark at 4°C. Do not freeze.
    Avoid prolonged exposure to light.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Flow Cytometry
  • Application Image
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 8794
  • Gene Name:
  • Gene Alias:
  • CD263,DCR1,LIT,MGC149501,MGC149502,TRAILR3,TRID
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq
  • Other Designations:
  • TNF related TRAIL receptor,TNF related apoptosis-inducing ligand receptor 3,TRAIL receptor 3,antagonist decoy receptor for TRAIL/Apo-2L,decoy receptor 1,decoy without an intracellular domain,lymphocyte inhibitor of TRAIL,tumor necrosis factor receptor sup
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