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Last updated: 2017/2/26
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IGF2R monoclonal antibody, clone MEM-238 (FITC)

  • Catalog # : MAB5071
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant IGF2R.
  • Immunogen:
  • Recombinant protein corresponding to IGF2R.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Primates
  • Specificity:
  • This antibody recognizes an epitope between domains 2 and 5 of CD222 (IGF2 receptor), a ubiquitously expressed 250 KDa multifunctional type I transmembrane protein.
  • Form:
  • Liquid
  • Conjugation:
  • FITC
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.2% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store in the dark at 4°C. Do not freeze.
    Avoid prolonged exposure to light.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Flow Cytometry
  • Application Image
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3482
  • Gene Name:
  • IGF2R
  • Gene Alias:
  • CD222,CIMPR,M6P-R,MPR1,MPRI
  • Gene Description:
  • insulin-like growth factor 2 receptor
  • Gene Summary:
  • The protein encoded by this gene is a receptor for both, insulin-like growth factor 2 (IGF2) and mannose 6-phosphate (M6P). The IGF2 and M6P binding sites are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of IGF2. In mice, the homologous gene is expressed only from the maternal chromosome. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000017536,cation-independent mannose-6 phosphate receptor,insulin-like growth factor-2 receptor (mannose-6-phosphate receptor, cation-independent)
  • Gene Pathway
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