IGF2R recombinant monoclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of Lane1:HepG2 whole cell lysate Lane2:SW480 whole cell lysate with IGF2R recombinant monoclonal antibody (Cat # RAB02713) at 1:1000 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using IGF2R recombinant monoclonal antibody (Cat # RAB02713). Counter stained with hematoxylin.
Immunocytochemistry
Immunocytochemical staining of HeLa cells using IGF2R recombinant monoclonal antibody (Cat # RAB02713)(green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton *100/PBS.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against IGF2R.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant IGF2R.
Theoretical MW (kDa)
274
Reactivity
Human, Mouse, Rat
Specificity
This antibody detects endogenous levels of IGF-2R and does not cross-react with related proteins.
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50-1:100)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Western Blot (1:1000-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.2 (50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at 4°C short term.
Aliquot and store at -20°C long term.
Avoid freeze-thaw cycles.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of Lane1:HepG2 whole cell lysate Lane2:SW480 whole cell lysate with IGF2R recombinant monoclonal antibody (Cat # RAB02713) at 1:1000 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using IGF2R recombinant monoclonal antibody (Cat # RAB02713). Counter stained with hematoxylin.Immunocytochemistry
Immunocytochemical staining of HeLa cells using IGF2R recombinant monoclonal antibody (Cat # RAB02713)(green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton *100/PBS.Immunofluorescence
Flow Cytometry
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Gene Info — IGF2R
Entrez GeneID
3482Protein Accession#
P11717Gene Name
IGF2R
Gene Alias
CD222, CIMPR, M6P-R, MPR1, MPRI
Gene Description
insulin-like growth factor 2 receptor
Omim ID
147280Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a receptor for both, insulin-like growth factor 2 (IGF2) and mannose 6-phosphate (M6P). The IGF2 and M6P binding sites are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of IGF2. In mice, the homologous gene is expressed only from the maternal chromosome. [provided by RefSeq
Other Designations
OTTHUMP00000017536|cation-independent mannose-6 phosphate receptor|insulin-like growth factor-2 receptor (mannose-6-phosphate receptor, cation-independent)
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Interactome
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Disease
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