TUBG1 monoclonal antibody, clone TU-32
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of TUBG1.
Immunogen
A synthetic peptide corresponding to amino acids 434-449 of human TUBG1.
Sequence
EYHAATRPDYISWGTQ
Host
Mouse
Theoretical MW (kDa)
48
Reactivity
Human
Specificity
This antibody recognizes an epitope (amino acids 434-449 in human) within C-terminus of TUBG1, a 48 KDa structural constituent of cytoskeleton and microtubule organizing center (MTOC).
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot
Immunocytochemistry
-
Gene Info — TUBG1
Entrez GeneID
7283Gene Name
TUBG1
Gene Alias
TUBG, TUBGCP1
Gene Description
tubulin, gamma 1
Omim ID
191135Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq
Other Designations
tubulin, gamma polypeptide
-
Interactome
-
Disease
-
Publication Reference
-
No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits.
Kniazeff J, Galvez T, Labesse G, Pin JP.
Journal of Neuroscience 2002 Sep; 22(17):7352.
-
Function of GB1 and GB2 subunits in G protein coupling of GABA(B) receptors.
Margeta-Mitrovic M, Jan YN, Jan LY.
PNAS 2001 Nov; 98(25):14649.
-
Gamma-aminobutyric acid type B receptors with specific heterodimer composition and postsynaptic actions in hippocampal neurons are targets of anticonvulsant gabapentin action.
Ng GY, Bertrand S, Sullivan R, Ethier N, Wang J, Yergey J, Belley M, Trimble L, Bateman K, Alder L, Smith A, McKernan R, Metters K, O'Neill GP, Lacaille JC, Hébert TE.
Molecular Pharmacology 2001 Jan; 59(1):144.
-
No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com