This antibody is highly reactive with desmin. On immunoblots, only the 52 KDa desmin band is stained. This antibody stains muscle cells in human tissues. No detectable reactivity with GFAP, keratin, vimentin or neurofilament.
Immunohistochemistry (1:100) The optimal working dilution should be determined by the end user.
In 150 mM PBS (0.09% sodium azide)
Store at 4°C.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq