FBN1 monoclonal antibody, clone RM463
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human FBN1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human FBN1.
Reactivity
Human
Specificity
This antibody reacts to human FBN1.
Form
Liquid
Purification
Protein A purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:100-1:200)
Western Blot (1:1000-1:25000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot (Tissue lysate) analysis of human plasma tissue lysates with FBN1 monoclonal antibody, clone RM463 (Cat # MAB23245) at a 1:2500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human breast with FBN1 monoclonal antibody, clone RM463 (Cat # MAB23245) at a 1:100 dilution.Immunohistochemistry
Immunohistochemical staining of formalin fixed and paraffin embedded human breast tissue sections using FBN1 monoclonal antibody, clone RM463 (Cat# MAB23245) at 1:100 dilution. -
Gene Info — FBN1
Entrez GeneID
2200Gene Name
FBN1
Gene Alias
FBN, MASS, MFS1, OCTD, SGS, WMS
Gene Description
fibrillin 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the fibrillin family. The encoded protein is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome. [provided by RefSeq
Other Designations
fibrillin 15
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Interactome
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Disease
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