FBN1 monoclonal antibody, clone CL0225
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot analysis of human tonsil tissue lysate with FBN1 monoclonal antibody, clone CL0225 (Cat # MAB15569).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with FBN1 monoclonal antibody, clone CL0225 (Cat # MAB15569) shows strong immunoreactivity in the extracellular matrix of seminiferous tubules.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human FBN1.
Immunogen
Recombinant protein corresponding to human FBN1.
Epitope
This antibody binds to an epitope located within the peptide sequence KMQCCCDAGRCWSPG as determined by overlapping synthetic peptides.
Sequence
DVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCEC
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG2b
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human tonsil tissue lysate with FBN1 monoclonal antibody, clone CL0225 (Cat # MAB15569).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with FBN1 monoclonal antibody, clone CL0225 (Cat # MAB15569) shows strong immunoreactivity in the extracellular matrix of seminiferous tubules. -
Gene Info — FBN1
Entrez GeneID
2200Protein Accession#
P35555Gene Name
FBN1
Gene Alias
FBN, MASS, MFS1, OCTD, SGS, WMS
Gene Description
fibrillin 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the fibrillin family. The encoded protein is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome. [provided by RefSeq
Other Designations
fibrillin 15
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Interactome
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Disease
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