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Last updated: 2021/8/8

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CLDN11 monoclonal antibody, clone AEDI-3 

  • Catalog # : MAB22283
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human CLDN11.
  • Immunogen:
  • A synthetic peptide corresponding to human CLDN11.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • The antibody reacts with human CLDN11, in native form and recombinant. Superfamily members of CLDN11 are not reactive to this antibody.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Flow Cytometry (1:100)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C for short term storage. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of SH-SY5Y cell lysate.
  • Flow Cytometry
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 5010
  • Gene Name:
  • CLDN11
  • Gene Alias:
  • OSP,OTM
  • Gene Description:
  • claudin 11
  • Gene Summary:
  • The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease. [provided by RefSeq
  • Other Designations:
  • oligodendrocyte transmembrane protein
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