CLDN11 monoclonal antibody, clone AEDI-3
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of SH-SY5Y cell lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human CLDN11.
Immunogen
A synthetic peptide corresponding to human CLDN11.
Host
Rabbit
Reactivity
Human
Specificity
The antibody reacts with human CLDN11, in native form and recombinant. Superfamily members of CLDN11 are not reactive to this antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:100)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C for short term storage. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of SH-SY5Y cell lysate.Flow Cytometry
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Gene Info — CLDN11
Entrez GeneID
5010Protein Accession#
O75508Gene Name
CLDN11
Gene Alias
OSP, OTM
Gene Description
claudin 11
Omim ID
601326Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease. [provided by RefSeq
Other Designations
oligodendrocyte transmembrane protein
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Interactome
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Pathway
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