CLDN11 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with CLDN11 polyclonal antibody (Cat # PAB30462) shows strong membranous positivity in cells in seminiferous ducts at 1:50-1:200 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human CLDN11.
Immunogen
Recombinant protein corresponding to human CLDN11.
Sequence
DAQAFGENRFYYTAGSSSPTHAKSAHV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human testis with CLDN11 polyclonal antibody (Cat # PAB30462) shows strong membranous positivity in cells in seminiferous ducts at 1:50-1:200 dilution. -
Gene Info — CLDN11
Entrez GeneID
5010Protein Accession#
O75508Gene Name
CLDN11
Gene Alias
OSP, OTM
Gene Description
claudin 11
Omim ID
601326Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease. [provided by RefSeq
Other Designations
oligodendrocyte transmembrane protein
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Interactome
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Pathway
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