IGF2BP3 monoclonal antibody, clone AEDB-9
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic protein of human IGF2BP3.
Immunogen
A synthetic peptide corresponding to human IGF2BP3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
This antibody reacts with human, mouse, rat IGF2BP3, in native form and recombinant. Superfamily members of IGF2BP3 are not reactive to antibody.
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (cell lysate) analysis of HeLa cell lysate. -
Gene Info — IGF2BP3
Entrez GeneID
10643Protein Accession#
O00425Gene Name
IGF2BP3
Gene Alias
DKFZp686F1078, IMP-3, IMP3, KOC1, VICKZ3
Gene Description
insulin-like growth factor 2 mRNA binding protein 3
Omim ID
608259Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq
Other Designations
IGF II mRNA binding protein 3|IGF-II mRNA-binding protein 3|KH domain containing protein overexpressed in cancer
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Interactome
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Disease
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