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PF4 monoclonal antibody, clone ACED-16 

  • Catalog # : MAB22089
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic protein of human PF4.
  • Immunogen:
  • A synthetic peptide corresponding to human PF4.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Rat
  • Specificity:
  • This antibody reacts with human, rat PF4, in native form and recombinant. Superfamily members of PF4 are not reactive to antibody.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-200)
    Immunoprecipitation (1:50)
    Western Blot (1:500-2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western Blot (tissue lysate) analysis of human spleen lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunoprecipitation
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 5196
  • Gene Name:
  • PF4
  • Gene Alias:
  • CXCL4,MGC138298,SCYB4
  • Gene Description:
  • platelet factor 4
  • Gene Summary:
  • Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990 [PubMed 1695112]).[supplied by OMIM
  • Other Designations:
  • chemokine (C-X-C motif) ligand 4,platelet factor 4 (chemokine (C-X-C motif) ligand 4)
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