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PTGS2 monoclonal antibody, clone RM348 

  • Catalog # : MAB21985
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against PTGS2.
  • Immunogen:
  • A peptide corresponding to C-terminus of human PTGS2.
  • Host:
  • Rat
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts to human COX-2 (Cyclooxygenase-2) (Prostaglandin G/H synthase 2).
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1000)
    Western Blot (1:1000-20000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (50% glycerol, 1% BSA, 0.09% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate) analysis of HeLa cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human lung cancer.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5743
  • Gene Name:
  • PTGS2
  • Gene Alias:
  • COX-2,COX2,GRIPGHS,PGG/HS,PGHS-2,PHS-2,hCox-2
  • Gene Description:
  • prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Gene Summary:
  • Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000033524,cyclooxygenase 2b,prostaglandin G/H synthase and cyclooxygenase,prostaglandin-endoperoxide synthase 2
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