IL17RA monoclonal antibody, clone 6H1B1
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Specifications
Product Description
Mouse monoclonal antibody raised against partial recombinant human IL17RA.
Immunogen
Recombinant protein corresponding to amino acids 33-320 of human IL17RA.
Host
Mouse
Theoretical MW (kDa)
96.1
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: IL17RA-hIgGFc transfected HEK293 cell lysates with IL17RA monoclonal antibody, clone 6H1B1 (Cat # MAB21444).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with IL17RA monoclonal antibody, clone 6H1B1 (Cat # MAB21444).Flow Cytometry
Flow cytometric analysis of HL-60 cells with IL17RA monoclonal antibody, clone 6H1B1 (Cat # MAB21444) (Green). Red: Negative Control. -
Gene Info — IL17RA
Entrez GeneID
23765Protein Accession#
Q96F46Gene Name
IL17RA
Gene Alias
CD217, CDw217, IL-17RA, IL17R, MGC10262, hIL-17R
Gene Description
interleukin 17 receptor A
Omim ID
605461Gene Ontology
HyperlinkGene Summary
Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq
Other Designations
interleukin 17A receptor
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Interactomes
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Pathways
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Diseases
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