IL17RA DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human IL17RA DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — IL17RA
Entrez GeneID
23765GeneBank Accession#
BC011624.2Protein Accession#
AAH11624.1Gene Name
IL17RA
Gene Alias
CD217, CDw217, IL-17RA, IL17R, MGC10262, hIL-17R
Gene Description
interleukin 17 receptor A
Omim ID
605461Gene Ontology
HyperlinkGene Summary
Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq
Other Designations
interleukin 17A receptor
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Interactome
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Pathway
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Disease
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