FCAMR monoclonal antibody, clone 5B1D12E1
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Specifications
Product Description
Mouse monoclonal antibody raised against partial recombinant human FCAMR.
Immunogen
Recombinant protein corresponding to amino acids 221-450 of human FCAMR.
Host
Mouse
Theoretical MW (kDa)
57.1
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: FCAMR-hIgGFc transfected HEK293 cell lysates with FCAMR monoclonal antibody, clone 5B1D12E1 (Cat # MAB21362).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with FCAMR monoclonal antibody, clone 5B1D12E1 (Cat # MAB21362).Flow Cytometry
Flow cytometric analysis of HL-60 cells with FCAMR monoclonal antibody, clone 5B1D12E1 (Cat # MAB21362) (Green). Red: Negative Control. -
Gene Info — FCAMR
Entrez GeneID
83953Protein Accession#
Q8WWV6Gene Name
FCAMR
Gene Alias
FCA/MR, FKSG87
Gene Description
Fc receptor, IgA, IgM, high affinity
Omim ID
605484Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the immunoglobulin receptor gene family involved in the microbial immune response. The protein localizes to the cell surface, where it functions as a receptor for IgM and IgA antibodies. The mouse homolog of this protein can bind and internalize IgM-coated particles, and mediates endocytosis of IgM-coated Staphylococcus by primary B lymphocytes. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Other Designations
Fc alpha/mu receptor|immunity related factor|receptor for Fc fragment of IgA and IgM
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Diseases
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