IGF2R monoclonal antibody, clone DIC-9
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More Files
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human IGF2R.
Immunogen
A synthetic peptide corresponding to human IGF2R.
Host
Rabbit
Theoretical MW (kDa)
274.375
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:100)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
Immunoprecipitation (1:30)
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Jurkat cell lysate with IGF2R monoclonal antibody, clone DIC-9 (Cat # MAB20463).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon with IGF2R monoclonal antibody, clone DIC-9 (Cat # MAB20463).Immunocytochemistry
Immunofluorescence
Immunoprecipitation
Flow Cytometry
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Gene Info — IGF2R
Entrez GeneID
3482Protein Accession#
P11717Gene Name
IGF2R
Gene Alias
CD222, CIMPR, M6P-R, MPR1, MPRI
Gene Description
insulin-like growth factor 2 receptor
Omim ID
147280Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a receptor for both, insulin-like growth factor 2 (IGF2) and mannose 6-phosphate (M6P). The IGF2 and M6P binding sites are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of IGF2. In mice, the homologous gene is expressed only from the maternal chromosome. [provided by RefSeq
Other Designations
OTTHUMP00000017536|cation-independent mannose-6 phosphate receptor|insulin-like growth factor-2 receptor (mannose-6-phosphate receptor, cation-independent)
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