DSG1 monoclonal antibody, clone ED-4
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More Files
- More Functions
Western Blot (Tissue lysate)
Western Blot analysis of human skin tissue lysate with DSG1 monoclonal antibody, clone ED-4 (Cat # MAB19991).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cervix cancer with DSG1 monoclonal antibody, clone ED-4 (Cat # MAB19991).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human DSG1.
Immunogen
A synthetic peptide corresponding to human DSG1.
Host
Rabbit
Theoretical MW (kDa)
113.748
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry
Immunofluorescence
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human skin tissue lysate with DSG1 monoclonal antibody, clone ED-4 (Cat # MAB19991).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cervix cancer with DSG1 monoclonal antibody, clone ED-4 (Cat # MAB19991).Immunocytochemistry
Immunofluorescence
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Gene Info — DSG1
Entrez GeneID
1828Protein Accession#
Q02413Gene Name
DSG1
Gene Alias
CDHF4, DG1, DSG
Gene Description
desmoglein 1
Gene Ontology
HyperlinkGene Summary
Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. [provided by RefSeq
Other Designations
desmosomal glycoprotein 1|pemphigus foliaceus antigen
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Interactome
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Disease
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