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Last updated: 2016/12/4
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MSLN monoclonal antibody, clone MB-G10

  • Catalog # : MAB1992
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant MSLN.
  • Immunogen:
  • Recombinant protein corresponding to extracellular region of human MSLN.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is directed against human mesothelin protein.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Recommend Usage:
  • Western Blot (1:1000)
    Immunohistochemistry (1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis of human MSLN recombinant protein at 100 ng (lane 1), 25 ng (lane 2), 6 ng (lane 3), 2 ng (lane 4) and 0.4 ng (lane 5) with MSLN monoclonal antibodies at 1:1000 dilution. Lane 6 contains 50 ng of human CDC25 recombinant protein.
    Top panel: Cat # MAB1993.
    Bottom panel: Cat # MAB1992.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human mesothelioma tissues with MSLN monoclonal antibodies at 1:100 dilution.
    Top panel: Cat # MAB1992.
    Bottom panel: Cat # MAB1993.
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Protein Accession#:
  • NP_005814;Q13421
  • Gene Name:
  • MSLN
  • Gene Alias:
  • CAK1,MPF,SMR
  • Gene Description:
  • mesothelin
  • Gene Summary:
  • An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • megakaryocyte potentiating factor
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