SMARCA4 monoclonal antibody, clone GFB-19

Catalog # MAB19675

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Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

Western Blot analysis of HeLa cell lysate with SMARCA4 monoclonal antibody, clone GFB-19 (Cat # MAB19675).

  • Specification

    Product Description

    Rabbit monoclonal antibody raised against synthetic peptide of human SMARCA4.

    Immunogen

    A synthetic peptide corresponding to human SMARCA4.

    Host

    Rabbit

    Theoretical MW (kDa)

    184.646

    Reactivity

    Human

    Form

    Liquid

    Purification

    Affinity purification

    Isotype

    IgG

    Recommend Usage

    ChIP
    Immunocytochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
    Immunoprecipitation (1:50)
    Western Blot (1:5000-1:20000)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).

    Storage Instruction

    Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    ChIP

    Western Blot (Cell lysate)

    Western Blot analysis of HeLa cell lysate with SMARCA4 monoclonal antibody, clone GFB-19 (Cat # MAB19675).

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunocytochemistry

    Immunofluorescence

    Immunoprecipitation

  • Gene Info — SMARCA4

    Entrez GeneID

    6597

    Protein Accession#

    P51532

    Gene Name

    SMARCA4

    Gene Alias

    BAF190, BRG1, FLJ39786, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2, hSNF2b

    Gene Description

    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

    Omim ID

    603254

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

    Other Designations

    ATP-dependent helicase SMARCA4|BRM/SWI2-related gene 1|SNF2-like 4|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4|brahma protein-like 1|global transcription activator homologous sequence|homeotic gene regulator|mitotic growth

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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