CCR7 monoclonal antibody, clone CFO-3
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More Files
- More Functions
Western Blot
Western Blot analysis of (1) Daudi, (2) MCF-7 cell lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human spleen.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human CCR7.
Immunogen
A synthetic peptide corresponding to human CCR7.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:50)
Immunocytochemistry (1:50-200)
Immunofluorescence (1:50-200)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-200)
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of (1) Daudi, (2) MCF-7 cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human spleen.Immunocytochemistry
Immunofluorescence
Immunoprecipitation
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Gene Info — CCR7
Entrez GeneID
1236Protein Accession#
P32248Gene Name
CCR7
Gene Alias
BLR2, CD197, CDw197, CMKBR7, EBI1
Gene Description
chemokine (C-C motif) receptor 7
Omim ID
600242Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. [provided by RefSeq
Other Designations
C-C chemokine receptor type 7|CC chemokine receptor 7|EBV-induced G protein-coupled receptor 1|Epstein-Barr virus induced G-protein coupled receptor|Epstein-Barr virus induced gene 1|MIP-3 beta receptor|chemokine (C-C) receptor 7|lymphocyte-specific G pro
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Interactome
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Pathway
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Disease
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