CAPN1 monoclonal antibody, clone 15C10
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Specification
Product Description
Mouse monoclonal antibody raised against native CAPN1.
Immunogen
Native purified human CAPN1.
Host
Mouse
Theoretical MW (kDa)
80
Reactivity
Bovine, Human, Mouse, Rat
Specificity
This antibody recognizes the 80 KDa subunit of micro-calpain as well as two smaller proteins that are presumed to be autolysis products.
Form
Liquid
Isotype
IgG1
Quality Control Testing
Antibody Reactive Against Native Purified Protein.
Recommend Usage
Western Blot (0.5-1.0 ug/mL)
ELISA (0.5-1.0 ug/mL)
Immunoprecipitation (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM sodium phosphate buffer, 150 mM NaCl, pH 7.5 (50% glycerol, 3 mM sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
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Gene Info — CAPN1
Entrez GeneID
823Gene Name
CAPN1
Gene Alias
CANP, CANP1, CANPL1, muCANP, muCL
Gene Description
calpain 1, (mu/I) large subunit
Omim ID
114220Gene Ontology
HyperlinkGene Summary
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. [provided by RefSeq
Other Designations
calcium-activated neutral proteinase|calpain 1, large subunit|calpain, large polypeptide L1|cell proliferation-inducing protein 30
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Interactome
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Pathway
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