GRIN2B monoclonal antibody, clone 6E9A8
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human GRIN2B.
Immunogen
Recombinant protein corresponding to amino acids 27-163 of human GRIN2B.
Host
Mouse
Theoretical MW (kDa)
166.4
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Immunofluorescence (1:100-1:500)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: GRIN2B-hIgGFc transfected HEK293 cell lysates with GRIN2B monoclonal antibody, clone 6E9A8 (Cat # MAB17961).Immunofluorescence
Immunofluorescent staining of HeLa cells with GRIN2B monoclonal antibody, clone 6E9A8 (Cat # MAB17961) (Green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.Enzyme-linked Immunoabsorbent Assay
ELISA analysis with GRIN2B monoclonal antibody, clone 6E9A8 (Cat # MAB17961).Flow Cytometry
Flow cytometric analysis of SK-N-SH cells with GRIN2B monoclonal antibody, clone 6E9A8 (Cat # MAB17961) (Green). Red: Negative Control. -
Gene Info — GRIN2B
Entrez GeneID
2904Protein Accession#
Q13224Gene Name
GRIN2B
Gene Alias
MGC142178, MGC142180, NMDAR2B, NR2B, hNR3
Gene Description
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
Omim ID
138252Gene Ontology
HyperlinkGene Summary
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq
Other Designations
N-methyl-D-aspartate receptor subunit 2B|glutamate receptor subunit epsilon-2
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