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Last updated: 2019/12/8
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CDH5 monoclonal antibody, clone 3D5C7 

  • Catalog # : MAB17795
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against recombinant human CDH5.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 29-223 of human CDH5 from E. coli.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 87.5
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Flow Cytometry (1:200-1:400)
    Immunocytochemistry
    Immunohistochemistry
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of (1) HUVE-12 cell, (2) A549 cell, (3) Mouse lung tissue, (4) NIH/3T3 cell with CDH5 monoclonal antibody.
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • ELISA analysis of CDH5 monoclonal antibody, clone 3D5C7.
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of HeLa cells with CDH5 monoclonal antibody (green) and negative control (purple).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1003
  • Gene Name:
  • CDH5
  • Gene Alias:
  • 7B4,CD144,FLJ17376
  • Gene Description:
  • cadherin 5, type 2 (vascular endothelium)
  • Gene Summary:
  • This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq
  • Other Designations:
  • 7B4 antigen,VE-cadherin,cadherin 5, type 2,cadherin 5, type 2, VE-cadherin (vascular epithelium),cd144 antigen,endothelial-specific cadherin,vascular endothelial cadherin
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