CDH5 monoclonal antibody
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis of CDH5 monoclonal antibody (Cat # MAB8745) at 1 : 2000 dilution interacts with recombinant CDH5 protein with a DsbA tag. Predicted band size : 51 KDa. Observed band size : 51 KDa.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant CDH5.
Immunogen
Recombinant protein corresponding to N-terminus residues of human CDH5.
Host
Mouse
Reactivity
Human
Specificity
This antibody is specific to CDH5.
Form
Liquid
Purification
Protein G purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:100-1:2000)
ELISA (1:5000-1:20000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis of CDH5 monoclonal antibody (Cat # MAB8745) at 1 : 2000 dilution interacts with recombinant CDH5 protein with a DsbA tag. Predicted band size : 51 KDa. Observed band size : 51 KDa.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CDH5
Entrez GeneID
1003GeneBank Accession#
NM_001795.3Gene Name
CDH5
Gene Alias
7B4, CD144, FLJ17376
Gene Description
cadherin 5, type 2 (vascular endothelium)
Omim ID
601120Gene Ontology
HyperlinkGene Summary
This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq
Other Designations
7B4 antigen|VE-cadherin|cadherin 5, type 2|cadherin 5, type 2, VE-cadherin (vascular epithelium)|cd144 antigen|endothelial-specific cadherin|vascular endothelial cadherin
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Interactome
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Pathway
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Disease
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