BAX monoclonal antibody, clone G26-R
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: mouse brain tissue lysate, Lane 2: rat brain tissue lysate, Lane 3: HEK293 cell lysate and GST-fusion recombinant protein (Lane 4: 100 ng, Lane 5: 200 ng and Lane 6: 500 ng) with BAX monoclonal antibody, clone G26-R (Cat # MAB15913).
Immunocytochemistry
Immunocytochemical staining of HEK293 cells with BAX monoclonal antibody, clone G26-R (Cat # MAB15913) at 1:200 dilution.
-
Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human BAX.
Immunogen
A synthetic peptide corresponding to amino acids 13-36 at N-terminus of human BAX.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
EVAC purification
Isotype
IgG
Recommend Usage
ELISA (1:30000-1:50000)
Immunocytochemistry
Immunoprecipitation
Western Blot (1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM Tris-HCl buffer, pH 8.0 (10 mg/mL BSA, 0.05% Sodium Azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot
Western Blot analysis of Lane 1: mouse brain tissue lysate, Lane 2: rat brain tissue lysate, Lane 3: HEK293 cell lysate and GST-fusion recombinant protein (Lane 4: 100 ng, Lane 5: 200 ng and Lane 6: 500 ng) with BAX monoclonal antibody, clone G26-R (Cat # MAB15913).Immunocytochemistry
Immunocytochemical staining of HEK293 cells with BAX monoclonal antibody, clone G26-R (Cat # MAB15913) at 1:200 dilution.Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
-
Gene Info — BAX
Entrez GeneID
581Protein Accession#
Q07812Gene Name
BAX
Gene Alias
BCL2L4
Gene Description
BCL2-associated X protein
Omim ID
600040Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq
Other Designations
apoptosis regulator BAX
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com