SNAI1 monoclonal antibody, clone CL3700
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Specifications
Product Description
Mouse monoclonal antibody raised against partial recombinant human SNAI1.
Immunogen
Recombinant protein corresponding to human SNAI1.
Sequence
MPRSFLVRKPSDPNRKPNYSELQDSNPE
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:5000-1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human breast cancer with SNAI1 monoclonal antibody, clone CL3700 (Cat # MAB15815) shows weak to moderate nuclear positivity in a subset of tumor cells. -
Gene Info — SNAI1
Entrez GeneID
6615Protein Accession#
O95863Gene Name
SNAI1
Gene Alias
SLUGH2, SNA, SNAH, dJ710H13.1
Gene Description
snail homolog 1 (Drosophila)
Omim ID
604238Gene Ontology
HyperlinkGene Summary
The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq
Other Designations
OTTHUMP00000031680|snail 1 homolog|snail 1 zinc finger protein|snail 1, zinc finger protein
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