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VPS26A monoclonal antibody, clone CL2287

  • Catalog # : MAB15737
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human VPS26A.
  • Immunogen:
  • Recombinant protein corresponding to human VPS26A.
  • Sequence:
  • LRKQRTNFHQRFESPESQASAEQPEM
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunofluorescence (1-4 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:500)
    Western Blot (1:200-1:500)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of U-251 MG cell lysate with VPS26A monoclonal antibody, clone CL2287 (Cat # MAB15737).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human fallopian tube with VPS26A monoclonal antibody, clone CL2287 (Cat # MAB15737) shows strong granular cytoplasmic immunoreactivity in glandular epithelium cells.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of MCF7 cells with VPS26A monoclonal antibody, clone CL2287 (Cat # MAB15737) (Green) shows distinct endosomes. Microtubule and nuclear probes are visualized in red and blue respectively (where available).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 9559
  • Gene Name:
  • VPS26A
  • Gene Alias:
  • FLJ12930,HB58,Hbeta58,PEP8A,VPS26
  • Gene Description:
  • vacuolar protein sorting 26 homolog A (S. pombe)
  • Gene Summary:
  • This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019721,vacuolar protein sorting 26 A
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