TTRAP monoclonal antibody, clone TDP2/1258
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Specifications
Product Description
Mouse monoclonal antibody raised against full length recombinant human TTRAP.
Immunogen
Recombinant protein corresponding to full length human TTRAP.
Host
Mouse
Theoretical MW (kDa)
41
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2b, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung carcinoma (A), human prostate carcinoma (B), human duodenal carcinoma (C) and human colon carcinoma (D) with TTRAP monoclonal antibody, clone TDP2/1258 (Cat # MAB14862).Immunofluorescence
Flow Cytometry
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Gene Info — TTRAP
Entrez GeneID
51567Protein Accession#
O95551Gene Name
TTRAP
Gene Alias
AD022, EAP2, MGC111021, MGC9099, dJ30M3.3
Gene Description
TRAF and TNF receptor associated protein
Omim ID
605764Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq
Other Designations
ETS1-associated protein 2|OTTHUMP00000016091|OTTHUMP00000039397|TRAF and TNF receptor-associated protein
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Interactomes
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Diseases
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Publication Reference
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EAPII interacts with ETS1 and modulates its transcriptional function.
Pei H, Yordy JS, Leng Q, Zhao Q, Watson DK, Li R.
Oncogene 2003 May; 22(18):2699.
Application:IF, IP, WB-Tr, Human, Monkey, COS-1, DU 145, Jurkat, SK-HEP-1 cells.
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EAPII interacts with ETS1 and modulates its transcriptional function.
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