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KRT6 monoclonal antibody, clone KRT6/1702

  • Catalog # : MAB14830
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant human KRT6.
  • Immunogen:
  • Recombinant protein corresponding to full length human KRT6.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 56
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • Flow Cytometry (0.5-1 ug/106 cells)
    Immunofluorescence (0.5-1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.1-0.2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS.
  • Storage Instruction:
  • Store at -20 to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human bladder carcinoma with KRT6 monoclonal antibody, clone KRT6/1702 (Cat # MAB14830).
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3853
  • Protein Accession#:
  • P02538;P04259;P48668
  • Gene Name:
  • KRT6A
  • Gene Alias:
  • CK6A,CK6C,CK6D,K6A,K6C,K6D,KRT6C,KRT6D
  • Gene Description:
  • keratin 6A
  • Gene Summary:
  • The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq
  • Other Designations:
  • 56 cytoskeletal type II keratin,K6D keratin,cytokeratin 6A,cytokeratin 6C,cytokeratin 6D,keratin 6C,keratin, epidermal type II, K6A,keratin, epidermal type II, K6C,keratin, type II cytoskeletal 6D,type II keratin isoform K6c
  • Gene Information
  • Entrez GeneID:
  • 3854
  • Protein Accession#:
  • P02538;P04259;P48668
  • Gene Name:
  • KRT6B
  • Gene Alias:
  • CK6B,K6B,KRTL1,PC2
  • Gene Description:
  • keratin 6B
  • Gene Summary:
  • The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq
  • Other Designations:
  • cytokeratin 6B,keratin, epidermal, type II, K6B,keratin, type II cytoskeletal 6B,keratin-like 1 (a type II keratin sequence)
  • Gene Information
  • Protein Accession#:
  • P02538;P04259;P48668
  • Gene Name:
  • KRT6C
  • Gene Alias:
  • K6E,KRT6E,MGC102925,MGC163455,MGC163457
  • Gene Description:
  • keratin 6C
  • Gene Summary:
  • Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. The type II keratins are clustered in a region of chromosome 12q13. [provided by RefSeq
  • Other Designations:
  • keratin 6E
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