KRT6A recombinant monoclonal antibody, clone 21E2
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human KRT6A.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human KRT6A.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry(1:50-1:200)
Immunofluorescence(1:20-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunofluorescence
Immunofluorescence staining of A549 Cells with KRT6A recombinant monoclonal antibody, clone 21E2 at 1:10, counter-stained with DAPI.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay Peak curve showing Hela cells stained with KRT6A recombinant monoclonal antibody, clone 21E2 (red line) at 1:50. -
Gene Info — KRT6A
Entrez GeneID
3853Protein Accession#
P02538Gene Name
KRT6A
Gene Alias
CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D
Gene Description
keratin 6A
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq
Other Designations
56 cytoskeletal type II keratin|K6D keratin|cytokeratin 6A|cytokeratin 6C|cytokeratin 6D|keratin 6C|keratin, epidermal type II, K6A|keratin, epidermal type II, K6C|keratin, type II cytoskeletal 6D|type II keratin isoform K6c
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