DSG2 monoclonal antibody, clone 8 E5
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human DSG2.
Immunogen
Recombinant protein corresponding to full length human DSG2.
Host
Mouse
Theoretical MW (kDa)
165
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (1-2 ug/mL)
Western Blotting (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunofluorescence
Flow Cytometry
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Gene Info — DSG2
Entrez GeneID
1829Protein Accession#
Q14126Gene Name
DSG2
Gene Alias
ARVC10, ARVD10, CDHF5, HDGC, MGC117034, MGC117036, MGC117037
Gene Description
desmoglein 2
Gene Ontology
HyperlinkGene Summary
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq
Other Designations
HDGC
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Interactome
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Pathway
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Disease
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