CDH2 monoclonal antibody, clone 13A9
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human CDH2.
Immunogen
Recombinant protein corresponding to cytoplasmic domain of human CDH2.
Host
Mouse
Theoretical MW (kDa)
130-140
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (1-2 ug/mL)
Western Blotting (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunofluorescence
Flow Cytometry
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Gene Info — CDH2
Entrez GeneID
1000Protein Accession#
P19022Gene Name
CDH2
Gene Alias
CD325, CDHN, CDw325, NCAD
Gene Description
cadherin 2, type 1, N-cadherin (neuronal)
Omim ID
114020Gene Ontology
HyperlinkGene Summary
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq
Other Designations
N-cadherin 1|cadherin 2, N-cadherin (neuronal)|cadherin 2, type 1|calcium-dependent adhesion protein, neuronal|neural cadherin
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Interactome
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Pathway
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Disease
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Publication Reference
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N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane.
Wahl JK 3rd, Kim YJ, Cullen JM, Johnson KR, Wheelock MJ.
The Journal of Biological Chemistry 2003 May; 278(19):17269.
Application:IF, IP, WB-Ce, Human, HeLa cells.
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N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane.
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