TOX3 monoclonal antibody, clone TOX3/1123
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Specifications
Product Description
Mouse monoclonal antibody raised against partial recombinant human TOX3.
Immunogen
Recombinant protein corresponding to 139 residues around amino acids 200-400 of human TOX3.
Host
Mouse
Theoretical MW (kDa)
63
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2b, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human gastric carcinoma (A), human gall bladder (B) and human cervical carcinoma (C) with TOX3 monoclonal antibody, clone TOX3/1123 (Cat # MAB14272).Immunofluorescence
Flow Cytometry
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Gene Info — TOX3
Entrez GeneID
27324Protein Accession#
O15405Gene Name
TOX3
Gene Alias
CAGF9, TNRC9
Gene Description
TOX high mobility group box family member 3
Omim ID
611416Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene
Other Designations
trinucleotide repeat containing 9
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Interactomes
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Diseases
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