TOX3 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TOX3.
Immunogen
A synthetic peptide corresponding to human TOX3.
Sequence
AGDPASLDFAQC
Host
Goat
Theoretical MW (kDa)
64.7
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:128000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — TOX3
Entrez GeneID
27324Protein Accession#
NP_001073899.1Gene Name
TOX3
Gene Alias
CAGF9, TNRC9
Gene Description
TOX high mobility group box family member 3
Omim ID
611416Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene
Other Designations
trinucleotide repeat containing 9
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Interactome
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Disease
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Publication Reference
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Genome-wide association study identifies novel breast cancer susceptibility loci.
Easton DF, Pooley KA, Dunning AM, Pharoah PD, Thompson D, Ballinger DG, Struewing JP, Morrison J, Field H, Luben R, Wareham N, Ahmed S, Healey CS, Bowman R, Meyer KB, Haiman CA, Kolonel LK, Henderson BE, Le Marchand L, Brennan P, Sangrajrang S, Gaborieau V, Odefrey F, Shen CY, Wu PE, Wang HC, Eccles D, Evans DG, Peto J, Fletcher O, Johnson N, Seal S, Stratton MR, Rahman N, Chenevix-Trench G, Bojesen SE, Nordestgaard BG, Axelsson CK, Garcia-Closas M, Brinton L, Chanock S, Lissowska J, Peplonska B
Nature 2007 Jun; 447(7148):1087.
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Genome-wide association study identifies novel breast cancer susceptibility loci.
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