FTH1 monoclonal antibody, clone 3F8
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human FTH1.
Immunogen
Recombinant His fusion protein corresponding to human FTH1.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Ammonium sulfate precipitation
Isotype
IgG2a, kappa
Recommend Usage
ELISA
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In HEPES, 0.15 M NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: U87 mg cell lysate and Lane 2: HeLa cell lysate with FTH1 monoclonal antibody, clone 3F8 (Cat # MAB12985).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with FTH1 monoclonal antibody, clone 3F8 (Cat # MAB12985) at 1:200 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — FTH1
Entrez GeneID
2495Protein Accession#
P02794Gene Name
FTH1
Gene Alias
FHC, FTH, FTHL6, MGC104426, PIG15, PLIF
Gene Description
ferritin, heavy polypeptide 1
Omim ID
134770Gene Ontology
HyperlinkGene Summary
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq
Other Designations
apoferritin|placenta immunoregulatory factor|proliferation-inducing protein 15
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Interactome
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Pathway
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Disease
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