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CEBPB monoclonal antibody, clone 21A1

  • Catalog # : MAB12916
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human CEBPB.
  • Immunogen:
  • Protein corresponding to amino acids 39-78 of human CEBPB.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
    Immunoprecipitation
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4.
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with CEBPB monoclonal antibody, clone 21A1 (Cat # MAB12916) at 10 ug/mL working concentration.
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 1051
  • Gene Name:
  • CEBPB
  • Gene Alias:
  • C/EBP-beta,CRP2,IL6DBP,LAP,MGC32080,NF-IL6,TCF5
  • Gene Description:
  • CCAAT/enhancer binding protein (C/EBP), beta
  • Gene Summary:
  • The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq
  • Other Designations:
  • CCAAT/enhancer binding protein beta,interleukin 6-dependent DNA-binding protein,liver-enriched transcriptional activator protein,nuclear factor of interleukin 6,transcription factor 5
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