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Last updated: 2016/11/27

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TH monoclonal antibody, clone 1D8

  • Catalog # : MAB12883
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant human TH.
  • Immunogen:
  • Recombinant protein corresponding to full length human TH.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunofluorescence (1:100)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
    Western Blot (1:4000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.3 (50% glycerol, 1% BSA, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of HEK293T cells transfected with the Lane 1: pCMV6-ENTRY control and Lane 2: pCMV6-ENTRY TH cDNA for 48 hrs (5 ug/lane) using TH monoclonal antibody, clone 1D8 (Cat # MAB12883).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate, nerve with TH monoclonal antibody, clone 1D8 (Cat # MAB12883).
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescent staining of COS-7 cells with TH monoclonal antibody, clone 1D8 (Cat # MAB12883) transiently transfected by pCMV6-ENTRY TH.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7054
  • Gene Name:
  • TH
  • Gene Alias:
  • TYH
  • Gene Description:
  • tyrosine hydroxylase
  • Gene Summary:
  • The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000011225,OTTHUMP00000011226,tyrosine 3-monooxygenase
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