TH monoclonal antibody, clone 1D8
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human TH.
Immunogen
Recombinant protein corresponding to full length human TH.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1
Recommend Usage
Immunofluorescence (1:100)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
Western Blot (1:4000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.3 (50% glycerol, 1% BSA, 0.02% sodium azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of HEK293T cells transfected with the Lane 1: pCMV6-ENTRY control and Lane 2: pCMV6-ENTRY TH cDNA for 48 hrs (5 ug/lane) using TH monoclonal antibody, clone 1D8 (Cat # MAB12883).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate, nerve with TH monoclonal antibody, clone 1D8 (Cat # MAB12883).Immunofluorescence
Immunofluorescent staining of COS-7 cells with TH monoclonal antibody, clone 1D8 (Cat # MAB12883) transiently transfected by pCMV6-ENTRY TH. -
Gene Info — TH
Entrez GeneID
7054Protein Accession#
P07101Gene Name
TH
Gene Alias
TYH
Gene Description
tyrosine hydroxylase
Omim ID
191290Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011225|OTTHUMP00000011226|tyrosine 3-monooxygenase
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Interactome
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