Western blot analysis of Lane 1: A431 cell line lysates Lane 2: A549 cell line lysates Lane 3: MCF-7 cell line lysates Lane 4: U-251 MG cell line lysates reacted with CAPN1 monoclonal antibody (Cat # MAB12351) at 1:1000 dilution.
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. [provided by RefSeq
calcium-activated neutral proteinase,calpain 1, large subunit,calpain, large polypeptide L1,cell proliferation-inducing protein 30