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BCL2L1 monoclonal antibody, clone SPM165

  • Catalog # : MAB12023
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of BCL2L1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 33-50 of mouse BCL2L1.
  • Sequence:
  • NRTEAPEGTESEMETPSA
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 27
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Immunohistochemistry (0.5-1 ug/mL)
    Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10mM PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of BCL2L1 in Jurkat cell lysate using BCL2L1 monoclonal antibody, clone SPM165 (Cat # MAB12023).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin-fixed paraffin-embedded sections) of Hodgkin's lymphoma with BCL2L1 monoclonal antibody, clone SPM165 (Cat # MAB12023).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 598
  • Gene Name:
  • BCL2L1
  • Gene Alias:
  • BCL-XL/S,BCL2L,BCLX,Bcl-X,DKFZp781P2092,bcl-xL,bcl-xS
  • Gene Description:
  • BCL2-like 1
  • Gene Summary:
  • The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000030550,OTTHUMP00000030551,OTTHUMP00000030553
  • Interactome
  • Interactome
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