MUC2 monoclonal antibody, clone CCP58
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Specification
Product Description
Mouse monoclonal antibody raised against MUC2.
Immunogen
The 23 amino acid VNTR region of human MUC2. This antibody is known to be specific to amino acids GTQTP.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG1
Recommend Usage
Western Blot (1:100-1:2000)
Flow Cytometry (1:10 - 1:1000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200 - 1:400)
Immunoprecipitation (1:10-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) analysis of human intestine (20x) with MUC2 monoclonal antibody, clone CCP58 (Cat # MAB11323) at 1:200 using peroxidase-conjugate and DAB chromogen.Immunoprecipitation
Flow Cytometry
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Gene Info — MUC2
Entrez GeneID
4583Gene Name
MUC2
Gene Alias
MLP, SMUC
Gene Description
mucin 2, oligomeric mucus/gel-forming
Omim ID
158370Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq
Other Designations
mucin 2|mucin 2, intestinal/tracheal|mucin-like protein
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Interactome
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Pathway
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Disease
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